Skin inflammatory (nontumor) – Erythema multiforme. erythema multiforme managed with prophylactic acyclovir. An year-old boy had .. Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y puesta al dia S, Marengo S. Eritema exudativo multiforme “minor. Request PDF on ResearchGate | On May 1, , V. Monsálvez and others published Eritema exudativo multiforme perinévico.

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Pathology Outlines – Erythema multiforme

In Bolognia, Dermatology, 2nd edn. Courtesy of Mark R. However, erythema multiforme may recur when the aciclovir is ceased. The face, neck and trunk are common sites.

Home About Us Advertise Amazon. The single most common trigger for developing erythema multiforme is herpes simplex virus HSV infectionusually herpes labialis cold sore on the lip and less often genital herpes.

Sign up for our Email Newsletters. There may be residual mottled skin discolouration. There is a genetic tendency to erythema nultiforme. Back Links pages that link to this page. Herpes simplex virus suppression and even prophylaxis with acyclovir has been shown to prevent recurrent erythema multiforme eruption.


Eritema multiforme

The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. Correlations between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: Palms and soles may be involved.

Updated by Dr Delwyn Dyall-Smith, Arch Dermatol ; CiteScore measures average citations received per document published. Click here for information on linking to our website or using our content or images.

Views Read Edit View history. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Erythema multiforme is divided into major and minor forms and is eeitema regarded as distinct from Stevens—Johnson syndrome SJS and toxic epidermal necrolysis TEN.

Erifema angioedema with eosinophilia Hereditary angioedema. It is an immune complex hypersensitivity reaction usually caused by drugs e. Erythemas Herpes simplex virus-associated diseases. Content is updated monthly with systematic literature reviews and conferences. Labs No lab tests are specific for Stevens Johnson Syndrome.

Erythema multiforme minor usually resolves spontaneously without scarring over 2—3 weeks. Continuing navigation will be considered as acceptance of this use.


It is also known as Fuchs syndromeand mucosal erythema multiforme may occasionally be due to recurrent herpes simplex. Many suspected aetiologic factors have been reported to cause EM. Many drugs have been reported to trigger erythema multiforme, including barbiturates, non-steroidal anti- inflammatory drugspenicillinssulphonamides, phenothiazines and anticonvulsants.

Related Bing Images Extra: Severe cutaneous adverse reactions. Toxic Epidermal Necrolysis C This is believed to be nearly always due to HSV-1 infection.

The typical target lesion also called iris lesion of erythema multiforme has a sharp margin, regular round shape and three concentric colour zones:. A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis.

Erythema multiforme

It often takes on the classical “target lesion” appearance, [4] with a pink-red ring around a pale center. Skin lesions are often grouped on elbows and knees.

Pediatr Dermatol ; The histology of erythema multiforme is characteristic but not diagnostic.